
Nanofat: Natural Rejuvenation with Stem Cells
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Reclaim your youthful radiance – without surgery!
Would you like not merely to conceal the signs of time, but to genuinely reverse them? To a degree, this is already possible today: with nanofat treatment, we use your own tissue not only to reduce the signs of ageing, but to fundamentally revitalise your skin. Wrinkle treatment
wrinkle treatment
with nanofat is one of the most advanced treatments in plastic surgery – and a further development of
autologous fat transfer
.
In nanofat, the individual particles are significantly smaller than in conventional
lipofilling
(microfat) and are rich in stem cells and growth factors. These set in motion a profound regeneration of the tissue. The skin becomes altogether younger, rosier and firmer – on the face, neck, décolletage or the backs of the hands. Wherever a gentle yet effective rejuvenation is desired.
You are choosing a treatment that not only works in a natural way, but also promises long-lasting results. This non-surgical treatment combines physiological processes with the latest technology to enhance your natural beauty. For us, aesthetics lie not solely in perfection, but in harmony.
Benefits of Nanofat Treatment
Revitalisation: Fresher, smoother and better-perfused skin (natural glow) – visible shortly after the first treatment.
Long-lasting: The improvements are generally permanent, as the skin is renewed at a deep level.
For sensitive, delicate skin: Ideal for sensitive areas such as the eyelids and lips.
Rejuvenation: A younger, fresher complexion and fewer fine lines. Ideal in combination with
Microneedling
for additional stimulation of collagen, elastin and
hyaluronic acid
.
What is Nanofat and how does it work?

Nanofat treatment is a groundbreaking variant of
autologous fat
treatment (
lipofilling
). Nanofat is based on a refined preparation process that allows us to obtain particularly small fat cells. These tiny particles contain high concentrations of mesenchymal stem cells (AdMSC). These cells possess growth-promoting properties and can regenerate the skin at a cellular level. You can think of it this way: the new, intact stem cells replace older and damaged cells. As a result, new, vital blood vessels form within the tissue, collagen production is stimulated, and circulation is enhanced.
A marked improvement in skin quality typically becomes visible after two to three months. The maximum effect – including wrinkle and scar reduction – is usually reached after approximately six months.
The Treatment Process
The treatment begins with the gentle harvesting of fat cells, usually from the abdomen or thigh area. The harvested fat is processed by centrifugation and filtration to isolate highly effective nanofat. This is then precisely introduced into the relevant facial areas.
The entire process significantly improves the quality of your skin – by stimulating collagen synthesis, markedly increasing elasticity, and comprehensively renewing the overall skin structure.
Areas of Application
Wrinkles and atrophic skin (aged skin)
Dark circles under the eyes
, including bluish discolouration of the skin
Uneven skin tone and acne scars
Dull, poorly perfused skin
Fine lines and creases, including around the mouth
Sunken cheeks following weight loss
How the Treatment Works
Nanofat treatment is minimally invasive and rarely takes longer than one hour. It is virtually pain-free – most of our patients are able to resume their normal activities as usual. Mild redness and swelling may occasionally occur, as with all medical-aesthetic treatments, and typically subside within a few hours.
Treatment costs start from €1,500.
Frequently asked questions
What results can be expected?
The results of a nanofat treatment are often long-lasting. They become visible in the weeks and months following the treatment, as the skin needs a little time to regenerate and renew itself fully. Many patients report a fresher, smoother skin surface that becomes apparent very soon after the treatment, along with a remarkably increased elasticity and the smoothing of fine lines and irregularities after a few months.
Is Nanofat treatment suitable for me?
The treatment is primarily suited to individuals who wish to improve their skin quality without undergoing invasive surgical procedures. It is particularly effective for early signs of skin ageing, minor skin irregularities, or when a natural and gentle alternative to synthetic fillers is desired.
What side effects may occur?
Typical side effects include mild swelling and redness at the injection sites. Bruising is rare, but should it occur, it will generally resolve on its own within a few days. In the days following treatment, please avoid irritating or over-stimulating the skin. Massages, sunbed sessions and sauna visits are also not recommended.
How safe is Nanofat treatment?
At our practice in Düsseldorf, we use only the highest-quality substances – and this applies equally to the processed autologous fat used in nanofat treatment. As the material is derived from the patient's own body, allergic reactions are virtually excluded. Infections and other complications are also highly unlikely, as the treatment is performed under very strict hygienic conditions. Should you have any concerns or questions, please do not hesitate to contact the Dr. Schuhmann practice at any time – or book your personal consultation here.
How does Nanofat differ from conventional fillers?
Unlike conventional fillers, which are often hyaluronic acid-based, nanofat is the patient's own fat, particularly rich in stem cells. These cells contribute to skin regeneration and enable the gentle filling of hollows and fine lines. In addition – and this is the key difference – they improve skin quality on a lasting basis. Conventional fillers do deliver immediate results, but these diminish again after a few months.
Are there alternatives to Nanofat treatment?
Alternatives may include other regenerative treatments such as PRP (platelet-rich plasma) or stem cell therapies, which also aim to improve skin quality. These methods utilise different aspects of the body's own regenerative capacity and may be appropriate depending on the skin condition and desired treatment outcome. Equally, for those seeking significant volume enhancement, autologous fat transfer (lipofilling) or additional filler or aesthetic treatments may be the more suitable option. To find out what is right for you, we recommend a personal consultation with Dr. Schuhmann in Düsseldorf.
What are the long-term benefits of the treatment?
In the long term, nanofat can contribute to a continuous improvement in skin elasticity and structure. The stimulated collagen synthesis and improved microcirculation can gradually lead to skin that looks and feels younger. This is not only of aesthetic benefit but is also advantageous for overall skin health.
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